This systematically organized and well-balanced book compresses within the covers of a single volume the theoretical principles and techniques involved in bio-separations, also called downstream processing. These techniques are derived from a range of subjects, for example, physical chemistry, analytical chemistry, bio-chemistry, biological science and chemical engineering.
Organized in its 15 chapters, the text covers in the first few chapters topics related to chemical engineering unit operations such as filtration, centrifugation, adsorption, extraction and membrane separation as applied to bioseparations. The use of chromatography as practiced at laboratory as well as industrial scale operation and related techniques such as gel filtration, affinity and pseudoaffinity chromatography, ion-exchange chromatography, electrophoresis and related methods have been discussed. The important applications of these techniques have also been highlighted.
• Basic principles involved in the various techniques are dealt with illustrative diagrams and description.
• Worked examples are given at the end of relevant chapters.
• An overview of entire course/subject of bio-separations is presented in Chapter 1.
The book is intended primarily as a textbook for undergraduate and postgraduate students of biotechnology-both in science and engineering. Some of the topics covered would also greatly benefit students who wish to specialize on certain areas as well as those in the industry engaged in biotechnology research.